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The researchers reported that a median of 3.19% of the epithelial cells in these normal breast tissues were aneuploid and over 82.67% had expanded copy number changes commonly found in invasive breast cancers.

Early loss of aneuploid embryos can direct maternal resources to healthier single newborns rather than twins or multiples.

Lurking in the background is the fear that using aneuploid or mosaic embryos could produce children with serious medical issues.

Genetic suppression of chromosomal instability markedly delays metastasis even in highly aneuploid tumour models, whereas continuous chromosome segregation errors promote cellular invasion and metastasis in a STING-dependent manner.

In follow-up papers, Chun and others found that full-grown aneuploid neurons were common in adult mouse brains, even forming circuits with other cells.