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In argyria, silver ions circulate through the bloodstream and become embedded in the dermis, a layer beneath the surface where the body cannot easily clear them.

They achieved both the hypodermis and dermis layers, with the epidermis forming within two weeks by itself.

As the skin undergoes photoaging, type I collagen bundles, which are found in the dermis beneath the top layer of the skin and provide strength and support to skin, become fragmented.

Multi-layered full thickness skin was created which contained all three layers present in normal human tissue: epidermis, dermis, and hypodermis.

“My skin is exposed and can burn in the sunlight because I don’t have that outer dermis,” he said.