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DNA methylation
- The modification of a strand of DNA after it is replicated, in which a methyl (CH 3 ) group is added to any cytosine molecule that stands directly before a guanine molecule in the same chain. Since methylation of cytosines in particular regions of a gene can cause that gene's suppression, DNA methylation is one of the methods used to regulate the expression of genes.
DNA methylation
- The chemical reactions that place a methyl group (a combination of one carbon atom and three hydrogen atoms) at a particular spot on DNA during organismal development. The effect of this process is probably to 鈥渢urn off鈥 various genes during the process of cellular differentiation , causing the cell to develop into a specific type.
Notes
Example Sentences
Evaluating the merits of these awards would require a deep understanding of dozens of scientific fields, from gravitational waves to DNA methylation.
When ProPublica informed Yao her $610,000 project was on the Senate committee鈥檚 list, she found it bizarre that such technical work on DNA methylation 鈥 a process that can affect cancer and neurological diseases 鈥 could be labeled as 鈥渨oke.鈥
The researchers found that the mothers with preeclampsia had 389 epigenetic modifications to areas known as DNA methylation regions.
Dr. Esteller explains that the team has obtained "the epigenetic profiles of the most extensive collection of cultured cells derived from transformed cells in the bloodstream, bone marrow, and lymph nodes up to date, examining in them over 800,000 sites of genome modification due to DNA methylation".
When the electrodes are removed, biological material such as RNA and DNA is analysed using advanced techniques like RNA sequencing and DNA methylation analysis.
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