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In our study, being able to control inflammation and preserve immunocompetence was associated with being asymptomatic.

Poor self-rated health could be a marker for immunocompetence, or the capacity of a person’s immune system to resist disease, the researchers said.

In 1992, a pair of biologists at the University of Tromsø in Norway proposed the “immunocompetence handicap hypothesis,” which essentially says that males will perform dumb, dangerous stunts to impress females.

The conference “Ageing and Immunity“ recently held in Siena, Italy, has reviewed and discussed several possible causes of immune senescence, as well as strategies for counteracting this waning of immune responsiveness and for restoring immunocompetence.

People who have high immunocompetence and low inflammation—by definition, the most protected group—live longer.