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PMDD, which is a severe cyclical, hormone-based mood disorder linked to periods, is thought to affect more than one in 20 women.

Diagnosed with anxiety and disruptive mood disorder, Sewell wrote in his journal that he felt as if he had fallen in love with a chatbot named after Daenerys Targaryen, a main character from the “Game of Thrones” television series.

It is unclear when Mavis was diagnosed, but the documents said that she was being treated for advanced dementia and a mood disorder.

In 2022 the committee in charge of the DSM restored the diagnosis of unspecified mood disorder for conditions that don’t fully meet the standards of depression or bipolar.

Leno in January filed a since-granted petition to become conservator of his wife’s person — including her medical decisions — after her diagnoses with advanced dementia and a mood disorder.