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They advocated that upcoming research projects address issues including "the role of viral neurotropism, host immune responses, and genetic factors in the development of such complications so that clinical management strategies can be developed."

The discovery and isolation of NGF, however, has provided an opportunity to reconsider the concept of neurotropism under more favorable experimental conditions.

Further evidence for a neurotropism mediated by NGF was provided by some elegant experiments done by Robert B. Campenot of the Harvard Medical School.