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In 1862 Pasteur placed it beyond reasonable doubt that the ammoniacal fermentation of urea is due to the action of a minute Schizomycete; in 1864 this was confirmed by van Tieghem, and in 1874 by Cohn, who named the organism Micrococcus ureae.

The cilia may be present during a short period only in the life of a Schizomycete, and their number may vary according to the medium on which the organism is growing.

The germinal cell then grows forth into the forms typical for the particular Schizomycete concerned.

Marchiafava and Celli have succeeded in demonstrating that the germs of this schizomycete attack directly the red blood-globules, and destroy them, causing them to undergo a series of very characteristic changes which admit of easy verification, and which render certain the existence of a malarial infection.

We felt ourselves justified in recognizing the malarial ferment in the schizomycete bacillus.